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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STIP1 All Species: 36.67
Human Site: Y316 Identified Species: 57.62
UniProt: P31948 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P31948 NP_006810.1 543 62639 Y316 S Y F K E E K Y K D A I H F Y
Chimpanzee Pan troglodytes XP_001163388 590 68062 Y363 S Y F K E E K Y K D A I H F Y
Rhesus Macaque Macaca mulatta XP_001115389 545 62710 Y318 S Y F K E E K Y K D A I H F Y
Dog Lupus familis XP_854960 543 62542 Y316 S Y F K E E K Y K D A I H F Y
Cat Felis silvestris
Mouse Mus musculus Q60864 543 62564 Y316 S Y F K E E K Y K D A I H F Y
Rat Rattus norvegicus O35814 543 62552 Y316 S Y F K E E R Y K D A I H F Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511150 518 59858 Y291 S Y F K E E K Y K E A I H F F
Chicken Gallus gallus
Frog Xenopus laevis NP_001080263 543 62088 N316 S Y F K E E K N K E A I Q F F
Zebra Danio Brachydanio rerio NP_001007767 542 61650 Y315 S Y F K Q E K Y K E A V Q F F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477354 490 55680 Y273 Y K Q A K V Y Y E K A M S E H
Honey Bee Apis mellifera XP_623766 485 55458 H275 Y E K S M S E H R T P E I K T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002329902 577 65196 Y344 M A R C S K D Y E R A I E T F
Maize Zea mays NP_001151932 581 65529 F348 L A K T S K D F D I A I E T Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_176461 571 64501 Y338 M A K V S K D Y E P V I Q T Y
Baker's Yeast Sacchar. cerevisiae P15705 589 66247 L352 A Y H K L G D L K K T I E Y Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 95 97.6 N.A. 97.4 97.6 N.A. 89.5 N.A. 86.7 80.1 N.A. 48.7 50.8 N.A. N.A.
Protein Similarity: 100 92 97.2 99.2 N.A. 98.9 98.9 N.A. 93.5 N.A. 93.9 91.5 N.A. 64.8 67.7 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 86.6 N.A. 73.3 66.6 N.A. 13.3 0 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 N.A. 86.6 93.3 N.A. 40 20 N.A. N.A.
Percent
Protein Identity: 46.1 45.7 N.A. 45.8 39.3 N.A.
Protein Similarity: 64.1 62.9 N.A. 64.8 57.5 N.A.
P-Site Identity: 20 20 N.A. 20 33.3 N.A.
P-Site Similarity: 40 33.3 N.A. 33.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 20 0 7 0 0 0 0 0 0 80 0 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 27 0 7 40 0 0 0 0 0 % D
% Glu: 0 7 0 0 54 60 7 0 20 20 0 7 20 7 0 % E
% Phe: 0 0 60 0 0 0 0 7 0 0 0 0 0 60 27 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 7 0 0 0 0 7 0 0 0 0 47 0 7 % H
% Ile: 0 0 0 0 0 0 0 0 0 7 0 80 7 0 0 % I
% Lys: 0 7 20 67 7 20 54 0 67 14 0 0 0 7 0 % K
% Leu: 7 0 0 0 7 0 0 7 0 0 0 0 0 0 0 % L
% Met: 14 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % P
% Gln: 0 0 7 0 7 0 0 0 0 0 0 0 20 0 0 % Q
% Arg: 0 0 7 0 0 0 7 0 7 7 0 0 0 0 0 % R
% Ser: 60 0 0 7 20 7 0 0 0 0 0 0 7 0 0 % S
% Thr: 0 0 0 7 0 0 0 0 0 7 7 0 0 20 7 % T
% Val: 0 0 0 7 0 7 0 0 0 0 7 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 14 67 0 0 0 0 7 74 0 0 0 0 0 7 60 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _